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Kamagra Oral Jelly Online - Analogs and Substitutes

Among the regulators of male potency the most popular is Viagra. But its main drawback is the high cost due to the incredible popularity. You can buy Kamagra online, which costs less than the well-known blue pills, but contains a similar active ingredient.

Main active ingredient

The drug Kamagra is manufactured by Centurion Laboratories and contains in its composition the active ingredient sildenafil. Viagra has similar composition. Sildenafil refers to phosphodiesterase-5 (PDE-5) inhibitors. The Kamagra is available in a form of a pill or jelly. Tablets contain 100 mg of the active substance, 4 pcs. in the package under the name "KAMAGRA-100 GOLD". Packaging "KAMAGRA ORAL JELLY" contains 7 sachets of jelly, each with 100 mg of sildenafil. The jelly form allows the drug to enter the bloodstream and begin to act in a matter of minutes.

Principle of action

The basis of the action of sildenafil is the suppression of the activity of the enzyme phosphodiesterase-5. This enzyme destroys cGMP involved in the development of erection. The drug increases the flow to the penis and contributes to the normal course of sexual arousal. With sexual arousal, the cells of the inner lining of the vessels in the penis start producing nitric oxide (NO). This substance stimulates the synthesis of guanylate cyclase and increases the concentration of cGMP. It causes relaxation of the vascular smooth muscle of the cavernous bodies in penis. As a result, the arteries are dilates, the blood flow increases, and it fills the cavernous bodies, as a result an erection appears. In the human body there are 11 types of PDE. Different forms of this enzyme are located in the myocardium, retina, skeletal muscles, and the walls of various vessels. Since Kamagra affects on all types of phosphodiesterase to some extent, this may lead to the development of some undesirable effects. Sildenafil is 10 times more strongly associates with PDE-5 than with PDE-6, 80 times stronger than PDE-1. With other subtypes of this enzyme, its affinity is 1000, 4000 times or more.

Indications

Kamagra is indicated in the next cases:

  • Erectile dysfunction of both organic and psychogenic origin;
  • Increased pressure in the small circle of blood circulation.

Contraindications

Kamagra should not be used in the next cases:

  • Erectile dysfunction of both organic and psychogenic origin;
  • Allergies to drugs with sildenafil in the composition;
  • Taking nitrates (nitroglycerin, nitrogranulong, isosorbide dinitrate, nitrospray, etc.).
The drug is extremely undesirable to use when:
  • Deformations of the penis of any origin (trauma, fibrosis, Peyronie's disease, etc.);
  • Propensity of priapism (uncontrolled pathological erection) of any origin (blood cancer pathology, sickle cell anemia, etc.);
  • Increased risk of bleeding;
  • Stages of acute gastric ulcer or duodenal ulcer;
  • Inherited retinal lesions;
  • Hepatic insufficiency of any origin;
  • Liver cirrhosis;
  • Severe renal failure;
  • Blood pressure level is more than 170/110 mm Hg;
  • The level of blood pressure is less than 90/50 mm Hg;
  • Heart attack, stroke, or intracranial hemorrhage;
  • Hemodynamically significant and life-threatening cardiac arrhythmias;
  • Heart failure;
  • Newly developed or progressive angina pectoris;
  • Usage of drugs that suppress the activity of cytochrome P450.

Side effects

The most frequently occurring side effects after the use of Kamagra (more than 2% of men) are:

  • Head pain;
  • Dizzyness;
  • Redness of the face and rush of blood to it;
  • Indigestion disorder;
  • Visual impairment, incl. abnormal color perception, light intolerance;
  • Obstruction of nasal breathing;
  • The development of infectious diseases from the urinary system;
  • Allergic reactions.
Among other undesirable effects, less often (less than in 2 men from 100) are observed:
  • Migraine pain;
  • Loss of consciousness;
  • Retinal hemorrhage;
  • Signs of coronary circulation failure;
  • Interruptions in heart rhythm;
  • Stroke;
  • Development of bronchial asthma;
  • Gastrointestinal bleeding;
  • Tendon ruptures;
  • Inflammatory reactions on the skin;
  • Allergic reactions.
The risk of developing undesirable effects from taking Kamagra is significantly increased if the rules for taking the drug or contraindications are not followed.

Instructions for use

If you already found where to buy cheap Kamagra (online or in pharmacy chains), then before using it, read the rules for taking the medicine. The treatment for enhancing the erection in the form of tablets should be taken 2-3 hours before the intended sexual intercourse, regardless of the meal. The drug is taken orally, not chewed and washed down with a moderate amount of water. The jelly dosage form is poured from the bag into the oral cavity and absorbed. It should be drunk 20-30 minutes before sex. Do not take more than 100 mg of Kamagra per day. Otherwise, increases the risk of undesirable effects. Interaction with other drugs While simultaneous use with nitrates increases the risk of a sharp uncontrolled drop in blood pressure levels. The simultaneous usage of sildenafil with drugs that inhibit cytochrome P450, increases the concentration of the drug to enhance erection and slows down its elimination from the body, which contributes to the development of side effects. These drugs include:

  • Macrolide antibiotics (azithromycin, clarithromycin, etc.);
  • Antifungal agents from the group of azoles (fluconazole, itraconazole, etc.);
  • Antidepressant fluoxetine;
  • Anti-arrhythmic and hypotensive agent diltiazem;
  • H2 blocker histamine receptor cimetidine;
  • Grapefruit juice.

Analogs and Substitutes

Generic Kamagra is much more available and cheaper than the popular blue pills. But if the developed effect does not satisfies you or undesirable reactions aroses, then you can try using other drugs to enhance erection with a similar mechanism of action. Medication with sildenafil in the composition Sildenafil is an active substance in Kamagra. Instead of this drug, you can try any other with a similar composition: Viagra, Maxigra, Sildenafil, Dynamic, Vizarsin, Vivaira, etc.

Levitra

The active substance in Levitra is vardenafil. It is more selectively associated with PDE-5, which leads to a significantly lower incidence of side effects from taking the drug. But the price or such benefits is a little bit higher. Only two drugs with such a composition are released: Levitra and Vardenafil.

Cialis and its generics

The most selective in relation to the inhibition of phosphodiesterase-5 is tadalafil. Of course, it is not a cheap Kamagra and it will cost a lot. The drug almost does not causes side effects like sildenafil does, it is more stronger as erectile dysfunction treatment and has a positive effect on the benign prostatic hyperplasia.

Buying without a prescription

According to the legislation, all drugs for the treatment of erectile dysfunction, including Kamagra, are being sold by prescription. However, in our pharmacy chains, especially on the network at specialized sites, the drug is freely available. If you have wondered, "where can I buy cheap Kamagra: online or in a pharmacy," then it is worth considering that the drug is rarely ordered for sale from a real counter. It will be much easier to find it on the network, where you can order it and receive it by mail.


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